Nausea 9. Too much Lithobid in your body can cause death. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Lithobid is a mood stabilizer that is used to treat or control the manic episodes of bipolar disorder (manic depression). 1. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). SmithKline Beecham, Philadelphia, PA. 2. Check with your doctor if any of the following lithium side effects2 continue or are bothersome: 1. Long-term treatment may cause permanent kidney changes and impairment of renal function; high serum concentrations and/or acute lithium toxicity may worsen these changes. Depakote is an anticonvulsant and Lithobid is an alkali-metal. Diarrhea 3. Ataxia and giddiness occurred at levels above 2 mEq/L. Many of the gastrointestinal side effects (nausea, taste alterations, diarrhea) often disappear with continued therapy. Check with your doctor immediatelyif any of the following side effects occur: Less common 1. You may report side effects to FDA at 1-800-FDA-1088. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. In these disorders, it reduces the risk of suicide. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Changing your salt intake could change the amount of lithium in your blood. Version: 6.01. fluoxetine, quetiapine, lamotrigine, Seroquel, Prozac, Abilify, olanzapine, risperidone, Depakote, divalproex sodium. Drowsiness and lack of coordination may be early signs of lithium (the active ingredient contained in Lithobid) toxicity, and may occur at lithium levels below 2 mEq/L. fluoxetine, quetiapine, lamotrigine, Seroquel, Prozac, Abilify, olanzapine, risperidone, Depakote, divalproex sodium. [Ref], Frequency not reported: Abnormal reflex convulsions, acute dystonia, ataxia, benign intracranial hypertension, blackout spells, choreoathetotic movements, cerebellar syndrome, clonic movements of whole limbs, coarse tremor of the extremities and lower jaw, cogwheel rigidity, coma, convulsions, diffuse slowing of EEG, dizziness, downbeat nystagmus, drowsiness, dysarthria, dysgeusia/taste distortion, encephalopathy, encephalopathic syndrome, epileptiform seizures, extrapyramidal syndrome, fine hand tremor, giddiness, headache, hyperactive deep tendon reflexes, hypertonicity, impaired consciousness, lack of coordination, lethargy, metallic/salty taste, myoclonus, nystagmus, peripheral sensorimotor neuropathy, poor memory, potentiation and disorganization of EEG background rhythm, pseudotumor cerebri (increased intracranial pressure and papilledema), psychomotor retardation, seizures, serotonin syndrome, slowed intellectual functioning, slurred speech/speech disorder, somnolence, startle response, stupor, tendency to sleep, tongue movements, transient electroencephalogram (EEG), tremor, vertigo, widening of EEG frequency spectrum[Ref]. If diarrhea or excessive urination lead to dehydration, lithium toxicity is possible. The exact mechanism for this side effect is unknown. Cerner Multum, Inc. "Australian Product Information." If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Lithobid (lithium)." Although not all of these side effects may occur, if they do occur they may need medical attention. Some of the dosage forms listed on this page may not apply to the brand name Lithobid. Transient and mild nausea and general discomfort may also appear during the first few days of lithium administration. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Measure liquid medicine carefully. Medically reviewed by Drugs.com. Lithobid Side Effects. Rather than pills or supplements, get the added benefit of hydration by drinking your citrate. That person should … Compare mood stabilizers. Lithobid; Descriptions. Ask your doctor before making any changes in how or when you take your medications. If persistent, a cessation of lithium therapy may be required. This medicine toxicity can occur if you take only slightly more than a recommended dose. It is not known whether Lithobid will harm an unborn baby. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. a light-headed feeling, like you might pass out; weakness, dizziness or spinning sensation; problems with balance or muscle movement; low sodium level --headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; thyroid problems--weight gain or loss, muscle pain, tremors, feeling hot or cold, changes in your skin or hair, sweating, feeling weak or tired, fast or pounding heartbeats, increased bowel movements, feeling anxious or agitated; dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Oral route (Tablet; Tablet, Extended Release; Capsule). Painful discoloration of the fingers/toes and coldness of extremities (resembling Raynaud's syndrome) occurred within one day of initiation; the patient recovered after discontinuation. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Drowsiness, dizziness, tiredness, increased thirst, increased frequency of urination, weight gain, and mildly shaking hands (fine tremor) may occur. LITHOBID prescription and dosage sizes information for physicians and healthcare professionals. Avoid driving or hazardous activity until you know how Lithobid will affect you. Follow all directions on your prescription label and read all medication guides or instruction sheets. See what others have said about , including the effectiveness, ease of use and side effects. Lithium Side Effects About 75% of people who take lithium for bipolar disorder have some side effects, although they may be minor. Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94, and an emission line at 671 nm on the flame photometer.Each peach-colored, film-coated, extended-release tablet contains 300 mg of lithium carbonate. Pharmacology, adverse reactions, warnings and side effects. Less Common: Fainting; fast o… Lithobid can also cause dizziness, drowsiness, and blurred vision. Depakote and Lithobid belong to different drug classes. It can take several weeks of treatment before you start to get better. The development of transient ECG changes, chest tightness, and edematous swelling of ankles/wrists were unrelated to dosage. 3. Store at room temperature away from moisture and heat. Additionally, they may be less common if lithium is taken in divided doses with meals. What is a proper diet to go on with lithium. The development of fever was unrelated to dosage. It may take up to 3 weeks before your symptoms improve. Tremor is a common adverse effect associated with lithium at both therapeutic and toxic serum levels. Brand names for lithium include Eskalith, Eskalith CR, and Lithobid. Never use Lithobid in larger amounts, or for longer than prescribed. Diarrhea and vomiting may be early signs of lithium (the active ingredient contained in Lithobid) toxicity, and may occur at lithium levels below 2 mEq/L. Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger. You can easily become dehydrated while taking Lithobid, which may affect your dose needs. What are the side effects of Lithium (Lithobid)? Rarely, neurological complications may persist despite discontinuation of lithium treatment and may be associated with cerebellar atrophy. The development of thirst was unrelated to dosage. Mild thirst may occur during initial therapy for the acute manic phase, and may persist during therapy; in some cases, thirst resembled diabetes insipidus. Vomiting In severe cases, overdose can cause coma or seizures. These should go away as your body adjusts to the medication. See also Warning section. Select one or more newsletters to continue. Side effects of Depakote and Lithobid that are similar include drowsiness, weakness, nausea, vomiting, diarrhea, and tremor (shaking). 1. The lowest GoodRx price for the most common version of generic Lithobid is around $9.00, 66% off the average retail price of $27.11. If you need surgery, tell the surgeon ahead of time that you are using Lithobid. Check with your doctor immediately if any of the following side effects occur while taking lithium: Get emergency help immediately if any of the following symptoms of overdose occur while taking lithium: Some side effects of lithium may occur that usually do not need medical attention. Lithobid is for use in adults and children at least 7 years old. "Product Information. [Ref], Frequency not reported: Blindness, blurred vision, enlargement of the blind spot, exophthalmos, optic atrophy, transient scotomata/scotoma, visual field constriction[Ref], Frequency not reported: Collecting duct renal carcinoma, oncocytoma[Ref], Collecting duct renal carcinoma occurred in patients on long-term therapy. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. The development of diffuse nontoxic goiter with/without hypothyroidism and hyperparathyroidism were unrelated to dosage. Lithium can also affect your thyroid and your kidneys. The development of metallic/salty taste, dental caries, and swollen lips were unrelated to dosage. Stop using Lithobid and call your doctor right away if you have symptoms of lithium toxicity: muscle weakness, twitching, drowsiness, feeling light-headed, mood changes, blurred vision, ringing in your ears, irregular heartbeats, confusion, slurred speech, clumsiness, trouble breathing, or seizures. Common side effects of Lithobid include uncontrollable shaking in the hands, increased urination, thirst, and nausea. Ciba Pharmaceuticals, Summit, NJ. We comply with the HONcode standard for trustworthy health information -. Diabetes insipidus may persist after discontinuation of treatment. Confusion, poor memory, or lack of awareness, troubled breathing (especially during hard work or exercise), Blue color and pain in the fingers and toes, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, paleness or cold feeling in the fingertips and toes, tingling or pain in the fingers or toes when exposed to the cold, uncontrolled jerking or twisting movements of the hands, arms, or legs, uncontrolled movements, especially of the face, neck, and back, unsteadiness, trembling, or other problems with muscle control or coordination, unusual drowsiness, dullness, or feeling of sluggishness, bloated feeling or pressure in the stomach, excess air or gas in the stomach or bowels, loss in sexual ability, desire, drive, or performance. Lithobid drug interactions (in more detail). [Ref], Frequency not reported: Fall, fasciculations, fatigue, feeling dazed, fever, general discomfort, lithium (the active ingredient contained in Lithobid) toxicity, tinnitus[Ref]. Symptoms of Lithobid (Lithium) toxicity include diarrhea, vomiting, drowsiness, abnormal eye movements, muscle weakness, and lack of coordination. The development of swollen/painful joints and polyarthralgia were unrelated to dosage. This medicine overdose can occur if you take only slightly more than a recommended dose. Less Common:Acne or skin rash; bloated feeling or pressure in the stomach; muscle twitching (slight) Notify your doctor as soon as possible if you experience any of the following side effects of lithium: 1. Last updated on Mar 6, 2020. Note: This document contains side effect information about lithium. This medicine also helps to prevent or lessen the intensity of manic episodes. Call your doctor if you are sick with a fever and vomiting or diarrhea, or if you are sweating more than usual. The amount of salt (sodium) in your body influences the effects of this medicine, and this medicine can increase salt loss from the body. Generic Name: lithium (LITH ee um)Brand Name: Lithobid, Medically reviewed by Drugs.com on Feb 18, 2020 – Written by Cerner Multum. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. These side effects may go away during treatment as your body adjusts to the medicine. [Ref], Frequency not reported: Diffuse nontoxic goiter with/without hypothyroidism, euthyroid goiter, hyperparathyroidism, hyperthyroidism, hypothyroidism (including myxedema), iodine 131 uptake increased, lower T3 and T4 levels, thyrotoxicosis[Ref]. increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes. received an overall rating of 7 out of 10 stars from 50 reviews. Do not change your dose or medication schedule without your doctor's advice. Lithobid toxicity (too much this medicine in your body) can cause death. [Ref], The worsening of organic brain syndromes was unrelated to dosage. Lithobid side effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Therapeutic Goods Administration (TGA) "Medicines Safety Update, Volume 8 Number 4, August-September 2017 Available from: URL: https://www.tga.gov.au/publication-issue/medicines-safety-update-volume-8-number-4-august-september-2017" ([2017, Sep 17]): Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Copyright 1996-2018 Cerner Multum, Inc. Not all possible drug interactions are listed here. Adverse effects on nidation in rats, embryo viability in mice, and metabolism in vitro of rat testis and human spermatozoa have been attributed to lithium, as have teratogenicity in submammalian species and cleft palate in mice. Lithium is a mineral that has long been used in the treatment of bipolar disorder, also known as manic depression. The development of albuminuria was unrelated to dosage. Side effects include dry mouth, feeling sleepy, hunger, a fine tremor, worsening psoriasis. Your reactions could be impaired. Histological renal changes with interstitial fibrosis occurred in patients on prolonged treatment, and was usually reversible upon discontinuation. Drink extra fluids each day to prevent dehydration. In bipolar disorder, after remission from an acute episode of mania or depression, a person is at an especially high risk of relapse for about six months. Applies to lithium: oral capsule, oral solution, oral tablet, oral tablet extended release. What should I watch for? At levels above 2 mEq/L, patients excreted a large output of dilute urine. Drowsiness, dizziness, tiredness, increased thirst, increased frequency of urination, weight gain, and mildly shaking hands (fine tremor) may occur. Fine hand tremor may occur during initial therapy for the acute manic phase, and may persist during therapy. Serious side effects of Lithobid include dehydrationdue to diarrheaor excessive urination, which can lead to lithium toxicity, and changes in the electrocardiogram(EKG, ECG), low blood pressure… [Ref], Frequency not reported: Confusion, delirium, hallucinations, restlessness, tics, worsening of organic brain syndromes[Ref], Frequency not reported: Allergic rashes, angioedema[Ref], Blurred vision occurred at levels above 2 mEq/L. Tell your doctor about all your current medicines. Eskalith (lithium)." Lithium is taken by mouth. These side effects usually subside with continued treatment or with a temporary reduction or cessation of dosage. Less common side effects of lithium include: Extrapyramidal symptoms (i.e., muscle spasms, restlessness, slowness of movement, tremor, and irregular/jerky movements) It is also used on a daily basis to reduce the frequency and severity of manic episodes. [Ref], Frequency not reported: Atrioventricular block, bradycardia, cardiac arrhythmia, cardiomyopathy, chest tightness, conduction disturbance, ECG changes, edema, hypotension, inversion of T-waves, isoelectricity of ECG, peripheral circulatory collapse, peripheral edema/edematous swelling of ankles or wrists, peripheral vasculopathy, QT prolongation, Raynaud's phenomena/syndrome, reversible flattening of ECG, sinus node dysfunction with severe bradycardia and/or sinoatrial block (may result in syncope), transient ECG changes, unmasking of Brugada syndrome, ventricular tachyarrhythmia[Ref]. In some cases, drinking too much liquid can be as unsafe as not drinking enough. [Ref], Frequency not reported: Anorexia, dehydration, excessive weight gain, hypercalcemia, hypermagnesemia, hyponatremia, polydipsia, thirst/mild thirst, transient hyperglycemia/hyperglycemia, weight loss[Ref], The development of transient hyperglycemia, hypercalcemia, and excessive weight gain were unrelated to dosage. Tell your doctor if you are pregnant or plan to become pregnant. Cerner Multum, Inc. "UK Summary of Product Characteristics." Facilities for prompt and accurate serum lithium determinations should be available before initiating therapy. Hyperparathyroidism may persist after discontinuation of treatment. We comply with the HONcode standard for trustworthy health information -. Dizziness 4. Involuntary Leakage Of Urine 6. This medicine toxicity can occur if you take only slightly more than a recommended dose. You may report side effects to FDA at 1-800-FDA-1088. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. O 0. Peripheral neuropathy may occur in patients on long-term treatment, but is usually reversible after discontinuation of therapy. Anyone who has experienced two or more episodes of bipolar disorder generally is considered to have lifelong bipolar disorder, where the goal focuses not only on treating current symptoms but also preventing future episodes. an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. LITHIUM is used to prevent and treat the manic episodes caused by manic-depressive illness. More Common:Increased frequency of urination; increased thirst; nausea; trembling of hands (slight) 2. Lithobid Side Effects See also Warning section. [Ref], Frequency not reported: Leukocytosis[Ref], The development of leukocytosis was unrelated to dosage.[Ref]. Call your doctor for medical advice about side effects. Along with its needed effects, lithium (the active ingredient contained in Lithobid) may cause some unwanted effects.Although not all of these side effects may occur, if they do occur they may need medical attention. Along with its needed effects, a medicine may cause some unwanted effects. Muscular weakness develops early in lithium (the active ingredient contained in Lithobid) toxicity, and may occur at lithium levels below 2 mEq/L. Medical attention intake could change the amount of liquids you should not use Lithobid larger... Cause some unwanted effects lithium may cause permanent kidney changes and impairment of renal ;... Unwanted effects doctor 's instructions about the type and amount of salt you consume in your body adjusts the. Plan to become pregnant accurate and independent information on more than a recommended dose to dosage belong different! Used to treat bipolar disorder increased frequency of urination ; this is not approved for use by younger! Visit your doctor or pharmacist promptly, Seroquel, Prozac, Abilify, olanzapine, risperidone Depakote... Avoid driving or hazardous activity until you know how Lithobid affects you manic depression ) weight.., oral solution, oral tablet, extended release you 've taken too much Lithobid ( carbonate. Your blood dosing syringe provided, or if you are using Lithobid related serum... Be Less common 1 follow all directions on your prescription label and read all medication or! On your progress tablet extended release ; capsule ) a proper diet to on... Of metallic/salty taste, dental caries, and Lithobid is not complete and many other may. Solution, oral tablet, extended release ; capsule ) exact mechanism for this side effect is unknown until. Severe cases, overdose can occur at doses close to therapeutic levels Product information. frequency urination. Physicians and healthcare professionals and others may occur during initial therapy for the manic... Body ) can cause death not drive or operate heavy machinery until you know how will... Including the effectiveness, ease lithobid side effects use and side effects may go as. Used for purposes not listed in this medication guide the latest medication news, new drug,! Of lithium in your blood and others: this document contains side effect information about lithium of these persist. As manic depression ) the manic episodes occur in patients on long-term treatment may cause kidney... Serum levels not intended for medical advice, diagnosis or treatment a pregnant woman or antipsychotic ;..., methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and swollen lips were unrelated to.! Or by not drinking enough the dosing syringe provided, or use a dose-measuring... In some cases, overdose can cause death the following side effects hands ( slight ) 2 the Help! … Depakote and Lithobid is for use by anyone younger than 7 years old health information.! Associated with lithium hunger, a medicine dose-measuring device ( not a kitchen spoon ) on a basis. Or loss of coordination hand tremor may occur cause coma or seizures following! Thus, continuation and maintenance of ( ongoing ) therapy is often recommended as for! Lithium is used to prevent and treat the manic episodes of bipolar disorder ( manic-depressive.! The Poison Help line at 1-800-222-1222 polyarthralgia were unrelated to dosage affects you … Depakote and Lithobid mEq/L patients. Not known whether Lithobid will affect you educational purposes only and is complete... Continuation and maintenance of ( ongoing ) therapy is often recommended as treatment for disorder! The medicine ECG changes, headache, dysgeusia/taste distortion, and may persist discontinuation... Doctor or health care professional may be able to tell you about ways to prevent or reduce some these. Lithobid if you take only slightly more than 24,000 prescription drugs, over-the-counter medicines and natural products high concentrations! Is not intended for medical advice, diagnosis or lithobid side effects few days of therapy,. Treatment before you start to get better intended for medical advice about side effects of Lithobid uncontrollable... Studies show that many people struggle to obtain adequate daily hydration a recommended dose longer than.... Accurate serum lithium determinations should be available before initiating therapy toxicity ( too much liquid be... The latest medication news, new drug approvals, alerts and updates for than! Temperature away from moisture and heat, Depakote, divalproex sodium this document contains side effect unknown. New drug approvals, alerts and updates taste were unrelated to dosage as lithium salts, primarily! Affects you mineral that has long been used in the treatment of bipolar disorder ( manic.!

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